At first sight, Prague can be a difficult city for a runner. Smooth jogging is interrupted by an unwelcome combination of sub-zero temperatures, cobblestones, and a surprising number of hills. I initially thought that only the truly hardy or downright foolish exercise outside in Prague after November. With a sub-two hour goal in mind, however, this year I have persevered and have some suggestions for running in Prague and preparing for race day, whatever the season.